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Dense Bodies of Human Cytomegalovirus Induce both Humoral and Cellular Immune Responses in the Absence of Viral Gene Expression

Infection of fibroblast cell cultures with human cytomegalovirus (HCMV) leads to the production of significant amounts of defective enveloped particles, termed dense bodies (DB). These noninfectious structures contain major antigenic determinants which are responsible for induction of both the humor...

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Detalhes bibliográficos
Main Authors: Pepperl, Sandra, Münster, Jürgen, Mach, Michael, Harris, J. Robin, Plachter, Bodo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112112/
https://ncbi.nlm.nih.gov/pubmed/10846097
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