Characterization of Stable, Soluble Trimers Containing Complete Ectodomains of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins

The human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins function as a membrane-anchored trimer of three gp120 exterior glycoproteins and three gp41 transmembrane glycoproteins. Previously, we reported three approaches to stabilize soluble trimers containing parts of the gp41 ectodomai...

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Bibliographic Details
Main Authors: Yang, Xinzhen, Farzan, Michael, Wyatt, Richard, Sodroski, Joseph
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC112061/
https://ncbi.nlm.nih.gov/pubmed/10823881
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