Polyvalent Envelope Glycoprotein Vaccine Elicits a Broader Neutralizing Antibody Response but Is Unable To Provide Sterilizing Protection against Heterologous Simian/Human Immunodeficiency Virus Infection in Pigtailed Macaques

The great difficulty in eliciting broadly cross-reactive neutralizing antibodies (NAbs) against human immunodeficiency virus type 1 (HIV-1) isolates has been attributed to several intrinsic properties of their viral envelope glycoprotein, including its complex quaternary structure, extensive glycosy...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Cho, Michael W., Kim, Young B., Lee, Myung K., Gupta, Kailash C., Ross, Will, Plishka, Ron, Buckler-White, Alicia, Igarashi, Tatsuhiko, Theodore, Ted, Byrum, Russ, Kemp, Chris, Montefiori, David C., Martin, Malcolm A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160726/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.5.2224-2234.2001
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