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A Yeast-Based Genetic System for Functional Analysis of Viral mRNA Capping Enzymes

Virus-encoded mRNA capping enzymes are attractive targets for antiviral therapy, but functional studies have been limited by the lack of genetically tractable in vivo systems that focus exclusively on the RNA-processing activities of the viral proteins. Here we have developed such a system by engine...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Ho, C. Kiong, Martins, Alexandra, Shuman, Stewart
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112033/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823853/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.12.5486-5494.2000
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