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A Yeast-Based Genetic System for Functional Analysis of Viral mRNA Capping Enzymes

Virus-encoded mRNA capping enzymes are attractive targets for antiviral therapy, but functional studies have been limited by the lack of genetically tractable in vivo systems that focus exclusively on the RNA-processing activities of the viral proteins. Here we have developed such a system by engine...

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Auteurs principaux: Ho, C. Kiong, Martins, Alexandra, Shuman, Stewart
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112033/
https://ncbi.nlm.nih.gov/pubmed/10823853
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