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Structure-Function Analysis of Hepatitis C Virus Envelope-CD81 Binding
Hepatitis C virus (HCV) is a major human pathogen causing chronic liver disease. We have recently found that the large extracellular loop (LEL) of human CD81 binds HCV. This finding prompted us to assess the structure-function features of HCV-CD81 interaction by using recombinant E2 protein and a re...
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Hauptverfasser: | , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Society for Microbiology
2000
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC112005/ https://ncbi.nlm.nih.gov/pubmed/10775621 |
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