Structure-Function Analysis of Hepatitis C Virus Envelope-CD81 Binding

Hepatitis C virus (HCV) is a major human pathogen causing chronic liver disease. We have recently found that the large extracellular loop (LEL) of human CD81 binds HCV. This finding prompted us to assess the structure-function features of HCV-CD81 interaction by using recombinant E2 protein and a re...

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Autori principali: Petracca, Roberto, Falugi, Fabiana, Galli, Giuliano, Norais, Nathalie, Rosa, Domenico, Campagnoli, Susanna, Burgio, Vito, Di Stasio, Enrico, Giardina, Bruno, Houghton, Michael, Abrignani, Sergio, Grandi, Guido
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC112005/
https://ncbi.nlm.nih.gov/pubmed/10775621
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