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Deletion of a Short, Untranslated Region Adjacent to the Polypurine Tract in Moloney Murine Leukemia Virus Leads to Formation of Aberrant 5′ Plus-Strand DNA Ends In Vivo

Experiments were performed to determine the function of a 28-nucleotide untranslated sequence lying between the envelope gene and the polypurine tract (PPT) sequence in the Moloney murine leukemia virus (Mo-MuLV) genome. A mutant virus carrying a deletion of this sequence (Mo-MuLVΔ28) replicated mor...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Bacharach, Eran, Gonsky, Jason, Lim, David, Goff, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.10.4755-4764.2000
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