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Multiple Antiviral Activities of Cyanovirin-N: Blocking of Human Immunodeficiency Virus Type 1 gp120 Interaction with CD4 and Coreceptor and Inhibition of Diverse Enveloped Viruses

Cyanovirin-N (CV-N) is a cyanobacterial protein with potent neutralizing activity against human immunodeficiency virus (HIV). CV-N has been shown to bind HIV type 1 (HIV-1) gp120 with high affinity; moreover, it blocks the envelope glycoprotein-mediated membrane fusion reaction associated with HIV-1...

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Udgivet i:J Virol
Principais autores: Dey, Barna, Lerner, Danica L., Lusso, Paolo, Boyd, Michael R., Elder, John H., Berger, Edward A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775592/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.10.4562-4569.2000
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