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An Evolutionarily Conserved Positively Charged Amino Acid in the Putative Membrane-Spanning Domain of the Foamy Virus Envelope Protein Controls Fusion Activity

Foamy viruses (FVs) are highly fusogenic, and their replication induces massive syncytium formation in infected cell cultures which is believed to be mediated by expression of the envelope (Env) protein. The FV Env is essential for virus particle egress. The unusually long putative membrane-spanning...

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Bibliographische Detailangaben
Hauptverfasser: Pietschmann, Thomas, Zentgraf, Hanswalter, Rethwilm, Axel, Lindemann, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111968/
https://ncbi.nlm.nih.gov/pubmed/10775583
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