An Evolutionarily Conserved Positively Charged Amino Acid in the Putative Membrane-Spanning Domain of the Foamy Virus Envelope Protein Controls Fusion Activity

Foamy viruses (FVs) are highly fusogenic, and their replication induces massive syncytium formation in infected cell cultures which is believed to be mediated by expression of the envelope (Env) protein. The FV Env is essential for virus particle egress. The unusually long putative membrane-spanning...

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הוצא לאור ב:	J Virol
Principais autores:	Pietschmann, Thomas, Zentgraf, Hanswalter, Rethwilm, Axel, Lindemann, Dirk
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Replication
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775583/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.10.4474-4482.2000
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