N-Linked Glycosylation of CXCR4 Masks Coreceptor Function for CCR5-Dependent Human Immunodeficiency Virus Type 1 Isolates

The chemokine receptors CXCR4 and CCR5 are the principal coreceptors for infection of X4 and R5 human immunodeficiency virus type 1 (HIV-1) isolates, respectively. Here we report on the unexpected observation that the removal of the N-linked glycosylation sites in CXCR4 potentially allows the protei...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Chabot, Donald J., Chen, Hong, Dimitrov, Dimiter S., Broder, Christopher C.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Assuntos:	Virus-Cell Interactions
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111957/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.9.4404-4413.2000
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