A Global Neutralization Resistance Phenotype of Human Immunodeficiency Virus Type 1 Is Determined by Distinct Mechanisms Mediating Enhanced Infectivity and Conformational Change of the Envelope Complex

We have described previously genetic characterization of neutralization-resistant, high-infectivity, and neutralization-sensitive, low-infectivity mutants of human immunodeficiency virus type 1 (HIV-1) MN envelope. The distinct phenotypes of these clones are attributable to six mutations affecting f...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Park, Eun Ju, Gorny, Miroslav K., Zolla-Pazner, Susan, Quinnan, Gerald V.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756031/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.9.4183-4191.2000
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