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A Global Neutralization Resistance Phenotype of Human Immunodeficiency Virus Type 1 Is Determined by Distinct Mechanisms Mediating Enhanced Infectivity and Conformational Change of the Envelope Complex

We have described previously genetic characterization of neutralization-resistant, high-infectivity, and neutralization-sensitive, low-infectivity mutants of human immunodeficiency virus type 1 (HIV-1) MN envelope. The distinct phenotypes of these clones are attributable to six mutations affecting f...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Park, Eun Ju, Gorny, Miroslav K., Zolla-Pazner, Susan, Quinnan, Gerald V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756031/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.9.4183-4191.2000
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