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Mechanisms of Human Papillomavirus E2-Mediated Repression of Viral Oncogene Expression and Cervical Cancer Cell Growth Inhibition

The papillomavirus E2 gene product plays a pivotal role in viral replication. E2 has multiple functions, including (i) transcriptional activation and repression of viral promoters and (ii) the enhancement of viral DNA replication. It was previously reported that E2 suppressed the growth of papilloma...

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Detalhes bibliográficos
Main Authors: Nishimura, Akiko, Ono, Takeshi, Ishimoto, Akinori, Dowhanick, Jennifer J., Frizzell, Margaret A., Howley, Peter M., Sakai, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111884/
https://ncbi.nlm.nih.gov/pubmed/10729150
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