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Mechanisms of Human Papillomavirus E2-Mediated Repression of Viral Oncogene Expression and Cervical Cancer Cell Growth Inhibition

The papillomavirus E2 gene product plays a pivotal role in viral replication. E2 has multiple functions, including (i) transcriptional activation and repression of viral promoters and (ii) the enhancement of viral DNA replication. It was previously reported that E2 suppressed the growth of papilloma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nishimura, Akiko, Ono, Takeshi, Ishimoto, Akinori, Dowhanick, Jennifer J., Frizzell, Margaret A., Howley, Peter M., Sakai, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111884/
https://ncbi.nlm.nih.gov/pubmed/10729150
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