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The T-Cell Receptor ζ Chain Contains Two Homologous Domains with Which Simian Immunodeficiency Virus Nef Interacts and Mediates Down-Modulation

We have recently demonstrated that simian immunodeficiency virus (SIV) Nef binds to the ζ chain of the T-cell receptor (TCR), leading to its down-modulation from T-cell surfaces (I. Bell, C. Ashman, J. Maughan, E. Hooker, F. Cook, and T. A. Reinhart, J. Gen. Virol. 79:2717–2727, 1998). Using a panel...

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Autori principali: Schaefer, Todd M, Bell, Ian, Fallert, Beth A., Reinhart, Todd A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC111828/
https://ncbi.nlm.nih.gov/pubmed/10708444
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