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Complex Effects of Deletions in the 5′ Untranslated Region of Primate Foamy Virus on Viral Gene Expression and RNA Packaging

Due to various advantageous features there is current interest in retroviral vectors derived from primate foamy viruses (PFVs). Two PFV cis-acting sequences have been mapped in the 5′ region of the RNA (pre-)genome and in the 3′ pol genomic region. In order to genetically separate PFV packaging cons...

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Udgivet i:J Virol
Principais autores: Heinkelein, Martin, Thurow, Jana, Dressler, Marco, Imrich, Horst, Neumann-Haefelin, Dieter, McClure, Myra O., Rethwilm, Axel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111814/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708430/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3141-3148.2000
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