Complex Effects of Deletions in the 5′ Untranslated Region of Primate Foamy Virus on Viral Gene Expression and RNA Packaging

Due to various advantageous features there is current interest in retroviral vectors derived from primate foamy viruses (PFVs). Two PFV cis-acting sequences have been mapped in the 5′ region of the RNA (pre-)genome and in the 3′ pol genomic region. In order to genetically separate PFV packaging cons...

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Main Authors: Heinkelein, Martin, Thurow, Jana, Dressler, Marco, Imrich, Horst, Neumann-Haefelin, Dieter, McClure, Myra O., Rethwilm, Axel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Gene Therapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC111814/
https://ncbi.nlm.nih.gov/pubmed/10708430
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