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Chimeric Dengue Type 2 (Vaccine Strain PDK-53)/Dengue Type 1 Virus as a Potential Candidate Dengue Type 1 Virus Vaccine

We constructed chimeric dengue type 2/type 1 (DEN-2/DEN-1) viruses containing the nonstructural genes of DEN-2 16681 virus or its vaccine derivative, strain PDK-53, and the structural genes (encoding capsid protein, premembrane protein, and envelope glycoprotein) of DEN-1 16007 virus or its vaccine...

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Autors principals: Huang, Claire Y.-H., Butrapet, Siritorn, Pierro, Dennis J., Chang, Gwong-Jen J., Hunt, Ann R., Bhamarapravati, Natth, Gubler, Duane J., Kinney, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC111800/
https://ncbi.nlm.nih.gov/pubmed/10708416
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