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Human T-Cell Leukemia Virus Type 2 Tax Mutants That Selectively Abrogate NFκB or CREB/ATF Activation Fail To Transform Primary Human T Cells

Human T-cell leukemia virus (HTLV) Tax protein has been implicated in the HTLV oncogenic process, primarily due to its pleiotropic effects on cellular genes involved in growth regulation and cell cycle control. To date, several approaches attempting to correlate Tax activation of the CREB/activating...

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Detalhes bibliográficos
Main Authors: Ross, Ted M., Narayan, Murli, Fang, Zhi-Yu, Minella, Alex C., Green, Patrick L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111754/
https://ncbi.nlm.nih.gov/pubmed/10684280
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