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The Decreased Replicative Capacity of Simian Immunodeficiency Virus SIVmac239Δnef Is Manifest in Cultures of Immature Dendritic Cells and T Cells

Transmission of simian immunodeficiency virus SIVmac239Δnef (Δnef) to macaques results in attenuated replication of the virus in most animals and ultimately induces protection against challenge with some pathogenic, wild-type SIV strains. It has been difficult, however, to identify a culture system...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Messmer, Davorka, Ignatius, Ralf, Santisteban, Christine, Steinman, Ralph M., Pope, Melissa
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666271/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2406-2413.2000
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