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The Enhancer I Core Region Contributes to the Replication Level of Hepatitis B Virus In Vivo and In Vitro

Chronic hepatitis B virus (HBV) infection can lead to liver cirrhosis and hepatocellular carcinoma. Long-term interaction of the immune system with the virus results in the selection of escape mutants and viral persistence. In this work we characterize mutations in the enhancer I region isolated pri...

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Detalhes bibliográficos
Main Authors: Bock, C.-Thomas, Malek, Nisar P., Tillmann, Hans L., Manns, Michael P., Trautwein, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111700/
https://ncbi.nlm.nih.gov/pubmed/10666249
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