Roscovitine, a Specific Inhibitor of Cellular Cyclin-Dependent Kinases, Inhibits Herpes Simplex Virus DNA Synthesis in the Presence of Viral Early Proteins

We have previously shown that two inhibitors specific for cellular cyclin-dependent kinases (cdks), Roscovitine (Rosco) and Olomoucine (Olo), block the replication of herpes simplex virus (HSV). Based on these results, we demonstrated that HSV replication requires cellular cdks that are sensitive to...

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הוצא לאור ב:	J Virol
Principais autores:	Schang, Luis M., Rosenberg, Amy, Schaffer, Priscilla A.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Virus-Cell Interactions
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666240/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2107-2120.2000
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