Pathogenic Conversion of Live Attenuated Simian Immunodeficiency Virus Vaccines Is Associated with Expression of Truncated Nef

Rhesus macaques infected with simian immunodeficiency virus (SIV) containing either a large nef deletion (SIVmac239Δ(152)nef) or interleukin-2 in place of nef developed high virus loads and progressed to simian AIDS. Viruses recovered from both juvenile and neonatal macaques with disease produced a...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Sawai, Earl T., Hamza, M. Sabry, Ye, Michael, Shaw, Karen E. S., Luciw, Paul A.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Pathogenesis and Immunity
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10644378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.4.2038-2045.2000
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