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Proteolytic Cleavage of the Fusion Protein but Not Membrane Fusion Is Required for Measles Virus-Induced Immunosuppression In Vitro

Immunosuppression induced by measles virus (MV) is associated with unresponsiveness of peripheral blood lymphocytes (PBL) to mitogenic stimulation ex vivo and in vitro. In mixed lymphocyte cultures and in an experimental animal model, the expression of the MV glycoproteins on the surface of UV-inact...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Weidmann, Armin, Maisner, Andrea, Garten, Wolfgang, Seufert, Marion, ter Meulen, Volker, Schneider-Schaulies, Sibylle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111676/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10644371/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.4.1985-1993.2000
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