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Activated Notch1 Modulates Gene Expression in B Cells Similarly to Epstein-Barr Viral Nuclear Antigen 2

Both Epstein-Barr viral nuclear antigen 2 (EBNA2) and activated Notch transactivate genes by interacting with the transcription factor RBP-Jκ. The viral protein EBNA2 may hence be regarded as a functional equivalent of an activated Notch receptor. Until now, nothing has been known about the physiolo...

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Detalhes bibliográficos
Main Authors: Strobl, Lothar J., Höfelmayr, Heike, Marschall, Gabriele, Brielmeier, Markus, Bornkamm, Georg W., Zimber-Strobl, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111648/
https://ncbi.nlm.nih.gov/pubmed/10644343
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