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B7 Costimulation Is Critical for Antibody Class Switching and CD8(+) Cytotoxic T-Lymphocyte Generation in the Host Response to Vesicular Stomatitis Virus
Antibody and cytotoxic T-lymphocyte (CTL) responses have critical roles in eliminating many viral infections. In addition to stimulation of the T-cell receptor, T cells require costimulatory signals to respond optimally. We evaluated the role of B7 costimulatory molecules (B7-1 and B7-2) in the immu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC111529/ https://ncbi.nlm.nih.gov/pubmed/10590107 |
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