B7 Costimulation Is Critical for Antibody Class Switching and CD8(+) Cytotoxic T-Lymphocyte Generation in the Host Response to Vesicular Stomatitis Virus
Antibody and cytotoxic T-lymphocyte (CTL) responses have critical roles in eliminating many viral infections. In addition to stimulation of the T-cell receptor, T cells require costimulatory signals to respond optimally. We evaluated the role of B7 costimulatory molecules (B7-1 and B7-2) in the immu...
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| Published in: | J Virol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111529/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10590107/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.1.203-208.2000 |
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