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Repeat Transduction in the Mouse Lung by Using Adeno-Associated Virus Vectors with Different Serotypes

Vectors derived from adeno-associated virus type 2 (AAV2) promote gene transfer and expression in the lung; however, we have found that while gene expression can persist for at least 8 months in mice, it was reduced dramatically in rabbits over a period of 2 months. The efficiency and persistence of...

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Bibliographische Detailangaben
Hauptverfasser: Halbert, Christine L., Rutledge, Elizabeth A., Allen, James M., Russell, David W., Miller, A. Dusty
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111488/
https://ncbi.nlm.nih.gov/pubmed/10627564
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