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Comparison of the UDP-N-Acetylmuramate:l-Alanine Ligase Enzymes from Mycobacterium tuberculosis and Mycobacterium leprae

In the peptidoglycan of Mycobacterium leprae, l-alanine of the side chain is replaced by glycine. When expressed in Escherichia coli, MurC (UDP-N-acetyl-muramate:l-alanine ligase) of M. leprae showed K(m) and V(max) for l-alanine and glycine similar to those of Mycobacterium tuberculosis MurC, sugge...

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Bibliografiske detaljer
Main Authors: Mahapatra, Sebabrata, Crick, Dean C., Brennan, Patrick J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111429/
https://ncbi.nlm.nih.gov/pubmed/11073931
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