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The Stringent Response of Mycobacterium tuberculosis Is Required for Long-Term Survival

The stringent response utilizes hyperphosphorylated guanine [(p)ppGpp] as a signaling molecule to control bacterial gene expression involved in long-term survival under starvation conditions. In gram-negative bacteria, (p)ppGpp is produced by the activity of the related RelA and SpoT proteins. Mycob...

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Detalhes bibliográficos
Main Authors: Primm, Todd P., Andersen, Susan J., Mizrahi, Valerie, Avarbock, David, Rubin, Harvey, Barry, Clifton E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111369/
https://ncbi.nlm.nih.gov/pubmed/10940033
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