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Characterization of the Enzymatic Component of Clostridium perfringens Iota-Toxin

The iota(a) component (i(a)) of Clostridium perfringens ADP ribosylates nonmuscle β/γ actin and skeletal muscle α-actin. Replacement of Arg-295 in i(a) with alanine led to a complete loss of NAD(+)-glycohydrolase (NADase) and ADP-ribosyltransferase (ARTase); that of the residue with lysine caused a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nagahama, Masahiro, Sakaguchi, Yoshihiko, Kobayashi, Keiko, Ochi, Sadayuki, Sakurai, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC111256/
https://ncbi.nlm.nih.gov/pubmed/10735850
Tagiau: Ychwanegu Tag
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