Characterization of the Enzymatic Component of Clostridium perfringens Iota-Toxin

The iota(a) component (i(a)) of Clostridium perfringens ADP ribosylates nonmuscle β/γ actin and skeletal muscle α-actin. Replacement of Arg-295 in i(a) with alanine led to a complete loss of NAD(+)-glycohydrolase (NADase) and ADP-ribosyltransferase (ARTase); that of the residue with lysine caused a...

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Bibliografske podrobnosti

izdano v:	J Bacteriol
Principais autores:	Nagahama, Masahiro, Sakaguchi, Yoshihiko, Kobayashi, Keiko, Ochi, Sadayuki, Sakurai, Jun
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Enzymes and Proteins
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10735850/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.8.2096-2103.2000
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