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The C108g Epitope in the V2 Domain of gp120 Functions as a Potent Neutralization Target When Introduced into Envelope Proteins Derived from Human Immunodeficiency Virus Type 1 Primary Isolates

Monoclonal antibodies (MAbs) directed against epitopes in the V2 domain of human immunodeficiency virus type 1 gp120 often possess neutralizing activity, but these generally are highly type specific, neutralize only laboratory isolates, or have low potency. The most potent of these is C108g, directe...

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Bibliographische Detailangaben
Hauptverfasser: Pinter, Abraham, Honnen, William J., D'Agostino, Paul, Gorny, Miroslaw K., Zolla-Pazner, Susan, Kayman, Samuel C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1112130/
https://ncbi.nlm.nih.gov/pubmed/15890930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.11.6909-6917.2005
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