Nitric Oxide Detoxification Systems Enhance Survival of Neisseria meningitidis in Human Macrophages and in Nasopharyngeal Mucosa

Nitric oxide (NO) contributes to mammalian host defense by direct microbicidal activity and as a signaling molecule of innate immune responses. Macrophages produce NO via the inducible NO synthase (iNOS). The genome of Neisseria meningitidis includes two genes, norB (encoding nitric oxide reductase)...

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Bibliographische Detailangaben
Hauptverfasser: Stevanin, TÂnia M., Moir, James W. B., Read, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1111883/
https://ncbi.nlm.nih.gov/pubmed/15908358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3322-3329.2005
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