Glycerol restores heat-induced p53-dependent apoptosis of human glioblastoma cells bearing mutant p53
BACKGROUND: We have previously reported that glycerol acts as a chemical chaperone to restore the expression of WAF1 in some human cancer cell lines bearing mutant p53. Since the expression of WAF1 is up-regulated by activated wildtype p53, glycerol appears to restore wtp53 function. The aim of the...
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| Publicado en: | BMC Biotechnol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111188/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11965244/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6750-2-6 |
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