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Novel Mechanism for Regulation of Epidermal Growth Factor Receptor Endocytosis Revealed by Protein Kinase A Inhibition

Current models put forward that the epidermal growth factor receptor (EGFR) is efficiently internalized via clathrin-coated pits only in response to ligand-induced activation of its intrinsic tyrosine kinase and is subsequently directed into a lysosomal-proteasomal degradation pathway by mechanisms...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Biol Cell
Principais autores: Salazar, Gloria, González, Alfonso
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Cell Biology 2002
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12006662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.01-08-0403
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