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Probing for Membrane Domains in the Endoplasmic Reticulum: Retention and Degradation of Unassembled MHC Class I Molecules

Quality control of protein biosynthesis requires ER-retention and ER-associated degradation (ERAD) of unassembled/misfolded molecules. Although some evidence exists for the organization of the ER into functionally distinct membrane domains, it is unknown if such domains are involved in the retention...

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Main Authors: Spiliotis, Elias T., Pentcheva, Tsvetelina, Edidin, Michael
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC111127/
https://ncbi.nlm.nih.gov/pubmed/12006653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-07-0322
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