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Utrophin Binds Laterally along Actin Filaments and Can Couple Costameric Actin with Sarcolemma When Overexpressed in Dystrophin-deficient Muscle

Dystrophin is widely thought to mechanically link the cortical cytoskeleton with the muscle sarcolemma. Although the dystrophin homolog utrophin can functionally compensate for dystrophin in mice, recent studies question whether utrophin can bind laterally along actin filaments and anchor filaments...

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Udgivet i:Mol Biol Cell
Principais autores: Rybakova, Inna N., Patel, Jitandrakumar R., Davies, Kay E., Yurchenco, Peter D., Ervasti, James M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111123/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12006649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.01-09-0446
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