Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis
Abstract Duchenne muscular dystrophy (DMD) is an X-linked genetic disorder resulting from mutations in the dystrophin gene. The mdx/utrn −/− mouse, lacking in both dystrophin and its autosomal homologue utrophin, is commonly used to model the clinical symptoms of DMD. Interestingly, these mice are i...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2017-08-01
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| Serier: | Scientific Reports |
| Online adgang: | https://doi.org/10.1038/s41598-017-05993-8 |
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