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Promising therapeutic approaches of utrophin replacing dystrophin in the treatment of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a serious genetic neuromuscular rare disease that is prevalent and caused by the mutation/deletion of the X-linked DMD gene that encodes dystrophin. Utrophin is a dystrophin homologous protein on human chromosome 6. Dystrophin and utrophin are highly homologous....

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Principais autores: Ruo Wu, Yafeng Song, Shiwen Wu, Yongchang Chen
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co. Ltd. 2022-11-01
Colecção:Fundamental Research
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S266732582200293X
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