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Endogenous oxidative DNA base modifications analysed with repair enzymes and GC/MS technique
GC/MS technique was used to identify endogenous levels of oxidatively modified DNA bases. To avoid possible artefact formation we used Fpg and Endo III endonucleases instead of acid hydrolysis to liberate the base products from unmodified DNA samples. Several different DNA preparations were used: (i...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2000
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC111057/ https://ncbi.nlm.nih.gov/pubmed/10684948 |
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