Effects of RNA secondary structure on cellular antisense activity
The secondary and tertiary structures of a mRNA are known to effect hybridization efficiency and potency of antisense oligonucleotides in vitro. Additional factors including oligonucleotide stability and cellular uptake are also thought to contribute to antisense potency in vivo. Each of these facto...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10684928/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.6.1340 |
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