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Mechanisms for Adaptation of Simian Immunodeficiency Virus to Replication in Alveolar Macrophages

In contrast to the simian immunodeficiency virus SIVmac239, which replicates poorly in rhesus monkey alveolar macrophages, a variant with nine amino acid changes in envelope (SIVmac239/316E) replicates efficiently and to high titer in these same cells. We examined levels of viral DNA, RNA, antigen,...

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Bibliografski detalji
Glavni autori: Mori, Kazuyasu, Rosenzweig, Michael, Desrosiers, Ronald C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110966/
https://ncbi.nlm.nih.gov/pubmed/11044136
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