Mechanisms for Adaptation of Simian Immunodeficiency Virus to Replication in Alveolar Macrophages

In contrast to the simian immunodeficiency virus SIVmac239, which replicates poorly in rhesus monkey alveolar macrophages, a variant with nine amino acid changes in envelope (SIVmac239/316E) replicates efficiently and to high titer in these same cells. We examined levels of viral DNA, RNA, antigen,...

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Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Mori, Kazuyasu, Rosenzweig, Michael, Desrosiers, Ronald C.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2000
Предметы:	Virus-Cell Interactions
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10852-10859.2000
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