Replication of Wild-Type and Mutant Human Cytomegalovirus in Life-Extended Human Diploid Fibroblasts

A cDNA encoding the catalytic subunit of human telomerase was used to generate life-extended derivatives of primary human diploid fibroblasts. The life-extended cells supported efficient human cytomegalovirus (HCMV) replication. A subclone of the life-extended cells was generated containing the HCMV...

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Bibliographic Details
Main Authors: Bresnahan, Wade A., Hultman, Gretchen E., Shenk, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110959/
https://ncbi.nlm.nih.gov/pubmed/11044129
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