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In Vivo Selection of Protease Cleavage Sites by Using Chimeric Sindbis Virus Libraries

Identifying protease cleavage sites contributes to our understanding of their specificity and biochemical properties and can help in designing specific inhibitors. One route to this end is the generation and screening of random libraries of cleavage sites. Both synthetic and phage-displayed librarie...

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Bibliografiska uppgifter
Huvudupphovsmän: Pacini, Laura, Vitelli, Alessandra, Filocamo, Gessica, Bartholomew, Linda, Brunetti, Mirko, Tramontano, Anna, Steinkühler, Christian, Migliaccio, Giovanni
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC110930/
https://ncbi.nlm.nih.gov/pubmed/11044100
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