Role of Murine Leukemia Virus Reverse Transcriptase Deoxyribonucleoside Triphosphate-Binding Site in Retroviral Replication and In Vivo Fidelity

Retroviral populations exhibit a high evolutionary potential, giving rise to extensive genetic variation. Error-prone DNA synthesis catalyzed by reverse transcriptase (RT) generates variation in retroviral populations. Structural features within RTs are likely to contribute to the high rate of error...

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Podrobná bibliografie

Vydáno v:	J Virol
Hlavní autoři:	Halvas, Elias K., Svarovskaia, Evguenia S., Pathak, Vinay K.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Replication
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11044079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.22.10349-10358.2000
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