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A Single Amino Acid Change in the Murine Leukemia Virus Capsid Gene Responsible for the Fv1(nr) Phenotype

The nr allele at the mouse Fv1 restriction locus governs resistance to B-tropic and some N-tropic murine leukemia viruses (MLVs). Sequence analysis and site-specific mutagenesis of N-tropic MLVs identified a single amino acid difference responsible for this restriction that is distinct from the site...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jung, Yong Tae, Kozak, Christine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110898/
https://ncbi.nlm.nih.gov/pubmed/10799620
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