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Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses

<p>Abstract</p> <p>Background</p> <p>We previously identified unusual variants of Moloney and Friend ecotropic mouse gammaretroviruses that have altered host range and are cytopathic in cells of the wild mouse species <it>Mus dunni</it>. Cytopathicity was attributed to different amino acid substitut...

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Bibliografiske detaljer
Principais autores: Wu Tiyun, Jung Yong T, Yan Yuhe, Kozak Christine A
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2008-01-01
Serier:Retrovirology
Online adgang:http://www.retrovirology.com/content/5/1/2
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