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Major Histocompatibility Complex Class I Gene Controls the Generation of Gamma Interferon-Producing CD4(+) and CD8(+) T Cells Important for Recovery from Friend Retrovirus-Induced Leukemia
Recovery from leukemia induced by Friend virus complex (FV) requires strong CD4(+) helper, CD8(+) cytotoxic T-lymphocyte, and B-cell responses. The development of these immune responses is dependent on the major histocompatibility complex (MHC) (H-2) genotype of the mouse. In H-2(b/b) mice, which sp...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC110893/ https://ncbi.nlm.nih.gov/pubmed/10799615 |
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